|
KMID : 0043319810040010043
|
|
Archives of Pharmacal Research
1981 Volume.4 No. 1 p.43 ~ p.51
|
|
|
Interaction of Flavins and Some Alcools on the Molecular Level
|
|
Yu BS
Chung HH/Lee SJ/Kim YB/Kim CK
|
|
|
Abstract
|
|
|
|
The effect of some alcohols on the riboflavin derivatives in non-polar solvent was studied by various spectroscopic method in order to support the viewpoint that alcohol may directly interact with the isoalloxazine moiety of FAD, the coenzyme of D-amino-acid oxidase. The most possible association complex between alcohol and riboflavin is the 1:1 complex through the 2-C carbonyl function of the isoalloxazine ring and the hydroxyl proton of alcohol. It is appeared that methanol has a larger association constant than any other alcohols, and the association constant decreases with the carbon number increases and being bulkier in the alkyl group of alcohols.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|